Actrapid 40IU Injection (Soluble Insulin) x10ml

Actrapid 40IU Injection contains human soluble insulin (biosynthetic r-DNA origin) as a neutral solution for injection. This short-acting insulin effectively controls blood glucose levels in diabetes patients and can be administered subcutaneously or intravenously.

Uses

Actrapid treats Type 1 and Type 2 diabetes mellitus requiring insulin therapy. It’s used for acute glycemic control, diabetic ketoacidosis management, perioperative glucose control, and as part of intensive insulin therapy regimens. Actrapid provides rapid glucose control when immediate insulin action is needed.

Benefits

• Provides rapid onset of glucose-lowering action
• Offers flexible dosing based on blood glucose levels
• Suitable for both subcutaneous and intravenous administration
• Effective in emergency diabetic situations
• Compatible with other insulin types for combination therapy
• Helps prevent diabetic complications through glucose control
• Allows precise titration for optimal glycemic management
• Biosynthetic human insulin reduces immunogenicity risk
• Essential for Type 1 diabetes survival

How It Works

Actrapid contains human insulin that mimics natural pancreatic insulin. It binds to insulin receptors on muscle and fat cells, facilitating glucose uptake and utilization. The medication also suppresses hepatic glucose production and promotes glycogen synthesis, effectively lowering blood glucose levels within 30 minutes of administration.

Dosage

Dosage is individualized based on blood glucose monitoring, meal timing, and patient response. Always follow healthcare provider instructions.

Duration of Action

Actrapid begins working within 30 minutes of subcutaneous injection, with peak action occurring 1-3 hours post-injection. Effects typically last 6-8 hours. Intravenous administration provides more rapid onset within 10-15 minutes but shorter duration, requiring continuous monitoring in clinical settings.

Side Effects

The most common side effect is hypoglycemia causing shakiness, sweating, confusion, or rapid heartbeat. Local injection site reactions include redness, swelling, or lipodystrophy. Some patients experience weight gain or allergic reactions. Severe hypoglycemia can cause unconsciousness or seizures requiring immediate treatment.

Warning

Never share Actrapid injection devices between patients due to infection risk. Always check insulin appearance before use – it should be clear and colorless. Monitor blood glucose regularly to prevent dangerous hypoglycemia. Actrapid requirements may change during illness, stress, pregnancy, or medication changes requiring medical supervision.

Pregnancy and Breastfeeding

Actrapid is safe during pregnancy and often preferred for gestational diabetes management. Insulin requirements typically increase during pregnancy, especially in the third trimester. It’s safe during breastfeeding but may require dosage adjustments. Regular monitoring is essential during pregnancy for optimal maternal and fetal outcomes.

Interaction

• Alcohol may increase hypoglycemia risk and mask symptoms
• Beta-blockers can hide hypoglycemic warning signs
• Corticosteroids may increase insulin requirements
• ACE inhibitors may enhance insulin sensitivity
• Some antibiotics can affect blood glucose levels
• Oral contraceptives may increase insulin needs

Precaution

Store unopened vials in refrigerator but never freeze. In-use vials can be kept at room temperature for 6 weeks. Rotate injection sites to prevent lipodystrophy. Monitor for signs of hypoglycemia, especially during exercise or delayed meals. Adjust doses during illness, travel across time zones, or medication changes.

Important Information

Actrapid is a prescription medication requiring proper training for safe administration. Always carry fast-acting glucose for hypoglycemia treatment. Inform all healthcare providers about insulin use before procedures or new medications. Regular blood glucose monitoring and medical follow-ups are essential for optimal diabetes management and preventing long-term complications.